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Thursday 18 April 2013

Is this the first tablet you can really type on? Researchers say new 'split' layout could make typing 30% faster

  • 19th century QWERTY keyboard ill suited to today's smartphones
  • New KALQ has 16 keys on the left and 12 keys on the right
  • Designers claim users can type 34 per cent faster with their product 

   Since it was introduced in the late 19th century the QWERTY keyboard has certainly stood the test of time, despite numerous challengers.
But the 1870s technology is ill-suited for today's tablets and other touch-screen devices when typing with the thumbs, expert say.
Experts at Germany’s Max Planck Institute for Informatics think they have found the answer. Called KALQ, this split-screen layout promises to make typing with the thumbs 34 per cent faster. 





Experts believe they have found the answer to the problem of typing with thumbs on tablet devices. Called KALQ, this split-screen layout is the latest challenger to the Qwerty keyboard 

Experts believe they have found the answer to the problem of typing with thumbs on tablet devices. Called KALQ, this split-screen layout is the latest challenger to the Qwerty keyboard
A research team led by Antto Oulasvirt used computational optimisation techniques along with a model of thumb movement to search through millions of potential layouts.
They decided upon a split layout with 16 keys on the left and 12 keys on the right. All vowels, with the exception of the Y -  sometimes considered a vowel - are located on the right along with G, K, L, Q and J.

Karma chameleon: Smart clothes that change their shape and colour as you move... and can even charge your phone

Clothes that change their colour and shape according to the wearer's movement have been developed by Canadian expert  

 The 'Karma Chameleon' project, launched by Concordia University in Montreal, weaves electronic fabric into clothes allowing the storage of energy from the body. The new lines by the team behind the innovation include a dress which can change shape and colour and a shirt which can charge a mobile phone

Tuesday 16 April 2013

Soon Your Bird Can Sing: Twitter to Release Music App

It sounds cool, but only a select few such as Ryan Seacrest get to play with Twitter’s music app for now. 

 

 
It’s not yet available to everyone, but Twitter’s giving a few hints about its forthcoming music app, which the social site is surely hoping will challenge music listening and sharing service Spotify.
Twitter’s music offering is likely to focus on social music recommendations–a move that would make sense considering its position as the second largest social network, popularity with musicians and music lovers, and the company’s purchase this week of a company that has been doing just that.
There is a hint of what’s coming here, where, as of Friday afternoon, Twitter’s iconic blue bird and the hashtag “music” dominated the page, along with the words “coming soon” and a log-in button. Pressing the button brought up a page asking you if you’d like to authorize “Twitter #music web” to use your Twitter account, giving it permission to read your timeline tweets, tweet on your behalf, view the list of people you follow, add followers, and update your profile. The description of the app promised “The best new music in the world right now”, but the service was not working.
It makes sense for Twitter to jump on the music, er, bandwagon: According to a Pew Research Center report, 67 percent of those who use social networking sites around the world share their opinions about music and movies on these sites. And Spotify, which offers a free and a paid version of its service, has been tapping into this by allowing users to share the songs they’re listening to with friends on sites like Facebook and Twitter, and to follow friends and artists within Spotify itself.
A few people are apparently already using it, including (apparently) American Idol host Ryan Seacrest, who has been tweeting about it. Various reports have suggested it will be available to all those with Twitter accounts soon.

What Bitcoin Is, and Why It Matters


Unlike other currencies, Bitcoin is underwritten not by a government, but by a clever cryptographic scheme.
For now, little can be bought with bitcoins, and the new currency is still a long way from competing with the dollar. But this explainer lays out what Bitcoin is, why it matters, and what needs to happen for it to succeed. Go over these...

A Smarter Algorithm Could Cut Energy Use in Data Centers by 35 Percent

New research suggests that data centers could significantly cut their electricity usage simply by storing fewer copies of files, especially videos.
For now the work is theoretical, but over the next year, researchers at Alcatel-Lucent’s Bell Labs and MIT plan to test the idea, with an eye to eventually commercializing the technology. It could be implemented as software within existing facilities. “This approach is a very promising way to improve the efficiency of data centers,” says Emina Soljanin, a researcher at Bell Labs who participated in the work. “It is not a panacea, but it is significant, and there is no particular reason that it couldn’t be commercialized fairly quickly.”
With the new technology, any individual data center could be expected to save 35 percent in capacity and electricity costs—about $2.8 million a year or $18 million over the lifetime of the center, says Muriel Médard, a professor at MIT’s Research Laboratory of Electronics, who led the work and recently conducted the cost analysis.

Moore’s Law and the Origin of Life

As life has evolved, its complexity has increased exponentially, just like Moore’s law. Now geneticists have extrapolated this trend backwards and found that by this measure, life is older than the Earth itself.

  Here’s an interesting idea. Moore’s Law states that the number of transistors on an integrated circuit doubles every two years or so. That has produced an exponential increase in the number of transistors on microchips and continues to do so. Continue reading...

Interview with BRAIN Project Pioneer: Miyoung Chun



The trickiest thing about the brain mapping project might be that we don’t even know what we’re trying to learn.
Brain Research through Advancing Innovative Neurotechnologies (BRAIN) project, which President Obama announced in his State of the Union address in February, will be a decade-long effort to understand the nature of thought (See “Why Obama’s Brain-Mapping Project Matters.”) The project, which inevitably evokes the Human Genome Project, will demand billions in research funding and require the coöperation of many government agencies, universities, and foundations. Miyoung Chun, a molecular geneticist and vice president for science programs at the Kavli Foundation, has been coördinating communication among those involved since planning began 18 months ago. Continue...

First Solar Shines as the Solar Industry Falters

First Solar’s strong finances are helping fund innovation and drive down the cost of solar power.



a solar cell

Innovation in solar cell technology has slowed as startups struggle to get a foothold in a tough market and solar panel manufacturers delay purchasing the equipment they need to manufacture more efficient cells. But First Solar, one of the world’s largest solar companies, continues to invest in boosting the efficiency of its solar cells.
The company, which is based in Tempe, Arizona, announced this week that it had set a new world record in efficiency for thin-film cadmium telluride solar panels. The equipment it uses to produce the record-setting panels will eventually be installed on all its production lines. It also announced the acquisition of Tetrasun, a startup with high-efficiency silicon technology that First Solar hopes to bring to market next year. First Solar’s stock jumped from $29 to over $40 on Tuesday and is still above $35 a share.

Thursday 11 April 2013

Iranian Inventor Claims To Have Created A Time Machine

An Iranian scientist has claimed to have created a working time machine, one that allows users to travel as far as eight years into the future.
time-machine-elite-daily-485x323
Ali Razeghi, a scientist from Tehran, has registered “The Aryayek Time Traveling Machine” with the state-run Center for Strategic Inventions.
According to Razeghi, 27, the device can predict the future and print out the results after taking a reading from the touch of a user.
Razaeghi says the device can “predict five to eight years of the future life of any individual, with 98 percent accuracy” thanks to a set of complex algorithms it runs on.

Tuesday 9 April 2013

One App’s iOS Debacle Shows Dangers of Betting It All on Apple

        A popular app gets yanked from Apple’s App Store, illustrating the danger of betting it all on one mobile OS. 



 

 AppGratis, an iOS app that offers users a free app each day that they’d normally have to pay for, is having a rough week. On Friday, Apple removed AppGratis from its app store, saying it ran afoul of two store guidlines: one banning apps that promote other apps, and another banning use of push notifications to send ads or direct marketing.

A Startup’s Nanowire Ink Lifts Solar Cell Efficiency

Sol Voltaics plans to make a nanowire-laden ink to boost solar panel efficiency using a rapid manufacturing process. 
 nanowires
   Ink filled with microscopic semiconductors called nanowires could make solar power cheaper by boosting the efficiency of solar panels by 25 percent, without adding much cost to manufacturing, says Sol Voltaics, a startup that has raised $11 million, and which this week announced its intention to commercialize the ink.
The ink is based on two advances from Lund University in Sweden. Professor Lars Samuelson demonstrated that nanowires can improve the efficiency of solar cells, and he developed a new way to manufacture nanowires that could make them practical to use.

AT&T Researchers Set a Long-Haul Data Record

 New optical technology paves the way for more efficient ocean-spanning transmissions.
 
    Researchers at AT&T have devised a way to increase the distance that large amounts of data can travel through a fiber-optic connection. The technique should allow 400-gigabit-per-second signals to travel for a distance of 12,000 kilometers—four times the previous distance possible—and it promises faster ocean-crossing transmission without adding more equipment. The feat is like sending 170 HD movies 12,000 kilometers—half-again as far as the distance from San Francisco to Tokyo.

A Cheap and Easy Plan to Stop Global Warming

Portrait of David Keith
Here is the plan. Customize several Gulfstream business jets with military engines and with equipment to produce and disperse fine droplets of sulfuric acid. Fly the jets up around 20 kilometers—significantly higher than the cruising altitude for a commercial jetliner but still well within their range. At that altitude in the tropics, the aircraft are in the lower stratosphere. The planes spray the sulfuric acid, carefully controlling the rate of its release. The sulfur combines with water vapor to form sulfate aerosols, fine particles less than a micrometer in diameter. These get swept upward by natural wind patterns and are dispersed over the globe, including the poles. Once spread across the stratosphere, the aerosols will reflect about 1 percent of the sunlight hitting Earth back into space. Increasing what scientists call the planet’s albedo, or reflective power, will partially offset the warming effects caused by rising levels of greenhouse gases.

Monday 8 April 2013

Facebook’s Real “Home” May be the Developing World

                     The new Facebook-centric Android app for smartphones builds on other efforts to court mobile users internationally.
http://www.investors.com/image/FB-IT16-040513-AP_345.jpg.cms
Facebook Home, a new collection of apps that makes the social network dominate Android phones, might have limited appeal to users already besieged with smartphone options—but it could fit nicely into Facebook’s efforts overseas, where the focus is on capturing first-time users.
The app lets Facebook lock the screens of Android smartphones and create a “cover feed” that fills those screens with status updates from Facebook friends. Strictly speaking, it is neither a “Facebook phone” nor a Facebook operating system, but it does create a Facebook-centric phone experience.
Some smartphone owners might roll their eyes (see “The Facebook Phone Is Finally Here, But Who Wants It?”), but Facebook’s real target may be those markets in which smartphone adoption is at an earlier stage of growth.

A Flexible Keyboard with Buttons That Feel Clickable

              Transparent, shape-changing plastics could make touch screens and keyboards that stimulate users’ sense of touch. 

Haptic Keyboard
A very thin keyboard that uses shape-changing polymers to replicate the feel and sound of chunky, clicking buttons could be in laptops and ultrabooks next year. Strategic Polymers Sciences, the San Francisco-based company that developed the keyboard, is working on transparent coatings that would enable this feature in touch screens.

The Paper-and-Pencil Cosmological Calculator

Ever struggled with the problem of converting redshift into parsecs, your worries are over thanks to a new cosmological distance chart based on the very latest data......

https://www.technologyreview.com/sites/default/files/images/Cosmo%20chart.png
Examine the light from a distant galaxy and you’ll notice that it is significantly different to light from nearby stars: its wavelength will be increased or shifted towards the red part of spectrum. This so-called redshift is the result of an object’s movement away from us–you can hear the same effect in the pitch of police car sirens when they move past us at speed.

Bill Gates Spreads his Battery Bets on Aquion

Aquion Energy lands $35 million to commercialize its novel grid-storage battery, bringing in Bill Gates as investor. 

                                            

When it comes to disruptive battery startups, one of the best endorsements you can get comes from software tycoon Bill Gates.
Aquion Energy has raised $35 million in a series D round, which brings Gates as a new investor. It’s at least the third energy storage startup that he has invested in. Others include Ambri, which is making a liquid metal battery, and LightSail Energy, which is using compressed air to store energy. If there’s a common thread to them, it’s that each company has taken a truly novel approach and are targeting grid-level storage, a technology considered crucial to using wind and solar at large scale.

Device Finds Stray Cancer Cells in Patients’ Blood

             A microfluidic device that captures circulating tumor cells could give doctors a noninvasive way to diagnose and track cancers. 

a microfluidic chip
Doctors typically diagnose cancer via a biopsy, which can be invasive and expensive. A better way to diagnose the disease would be to detect telltale tumor cells floating in the bloodstream, but such a test has proved difficult to develop because stray cancer cells are rare, and it’s difficult to separate them from the mélange of cells in circulation.
Now researchers from Massachusetts General Hospital and Harvard Medical School say they’ve built a microfluidic device that can quickly grab nearly any type of tumor cell, an advance that may one day lead to simple blood tests for detecting or tracking cancer.

The Microsoft CEO explains the strategy behind his company’s most ambitious and strangest major product.

http://www.mediasyndicator.com/blog/wp-content/uploads/2012/11/event_ballmerWin8Launch_Print.jpg 
Windows 8, the most recent version of Microsoft’s operating system, is the most ambitious and the strangest major product ever released by the software giant. Designed to run on smartphones, tablet computers, laptops, servers, and even supercomputers, Windows 8 presents its users with the same interface, with only minor variations, on any device. In order to demonstrate to customers and original equipment manufacturers (OEMs) the possibilities of the new interface, which is radically different from any previous version of Windows and optimized for touch, Microsoft was compelled to develop its first computer, the Surface tablet. The response has been mixed: some critics guardedly welcomed Windows 8, praising its gorgeous graphic design and daring indifference to Microsoft’s past; still others were baffled by the attempt to impose a single user experience onto all types of computers (see our own review, “Windows 8: Design over Usability,” by Simson Garfinkel). Jason Pontin, MIT Technology Review’s editor in chief, spoke to Microsoft’s chief executive, Steve Ballmer, about the new operating system and the future of his company.

Seeing the same graphical user interface across platforms is a wondrous thing, but it’s also a little like seeing a bear on a bike. Why do it at all?
For the first time, Windows PCs, tablets, and phones, as well as Xbox, all share the same look and feel and iconic live tiles. A common visual language makes a lot of sense and helps unify the experiences people have across the devices and services they use daily. Increasingly, people access the same content and services from multiple devices or use more than one device at a time. SmartGlass is really magical in this way. You can cue a movie from your Windows tablet to play on the TV connected to your Xbox, or navigate the Web on the TV screen with your Windows Phone. The same look and feel shortens the learning curve and creates a more seamless user experience. Beyond just sharing the same look, more and more we’re sharing technology across all Windows devices and Xbox. They all connect to SkyDrive—our cloud storage solution—and IE, and for the first time, Windows Phone now shares the same core as Windows PCs and tablets. We see incredible benefits for our customers and developers with this approach.#
 More questions after the cut.....

Facebook Home: A Social Smartphone Makeover

      A modified version of Android puts social networking, and Facebook, at the heart of a device. 

SOURCE: MIT Technology

screen shot of chat on smartphone 
MIT Technology Review editor Rachel Metz live-blogged Facebook’s announcement from its headquarters in Menlo Park, California. Read her blow-by-blow account of the event after the cut.

Can Small Reactors Ignite a Nuclear Renaissance?


Small, modular nuclear reactor designs could be relatively cheap to build and safe to operate, and there’s plenty of corporate and government momentum behind a push to develop and license them. But will they be able to offer power cheap enough to compete with natural gas? And will they really help revive the moribund nuclear industry in the United States?
Last year, the U.S. Department of Energy announced that it would provide $452 million in grants to companies developing small modular reactors, provided the companies matched the funds (bringing the total to $900 million). In November it announced the first grant winner—Babcock & Wilcox, a maker of reactors for nuclear ships and submarines—and this month it requested applications for a second round of funding. The program funding is expected to be enough to certify two or three designs.
The new funding is on top of the hundreds of millions of dollars Babcock & Wilcox has already spent on developing its 180-megawatt reactor design, along with a test facility to confirm its computer models of the reactor. Several other companies have also invested in small modular reactors, including Holtec, Westinghouse Electric, and the startup NuScale, which is supported by the engineering firm Fluor (see “Small Nukes Get a Boost,” “Small Nuclear Reactors Get a Customer,” and “Giant Holes in the Ground”).
The companies are investing in the technology partly in response to requests from power providers. One utility, Ameren Missouri, the biggest electricity supplier in that state, is working with Westinghouse to help in the certification process for that company’s small reactor design. Ameren is particularly worried about potential emissions regulations, because it relies on carbon-intensive coal plants for about 80 percent of its electricity production.
As Ameren anticipates shutting down coal plants, it needs reliable power to replace the baseload electricity they produce. Solar and wind power are intermittent, requiring fossil-fuel backup, notes Pat Cryderman, the manager for nuclear generation development at Ameren. “You’re really building out twice,” he says. That adds to the costs. And burning the backup fuel, natural gas, emits carbon dioxide.
Nuclear reactors that generate over 1,000 megawatts each can cost more than $10 billion to build, an investment that’s extremely risky for a company whose total assets are only $23 billion. Power plants based on small modular reactors, which produce roughly 200 to 300 megawatts, are expected to cost only a few billion dollars, a more manageable investment. “They’re simply more affordable,” says Robert Rosner, coauthor of a University of Chicago study of potential costs that the DOE has drawn on in evaluating the potential of small reactors.
The smaller size has other potential advantages. Siting a large nuclear power plant can be difficult—it requires, for example, an emergency planning zone extending 10 miles around the plant, Cryderman says. That zone could be as small as half a mile for a small modular reactor—in part because of its size and in part because the reactors have added design features. For example, while the newest reactors—such as the Westinghouse AP1000—are designed to keep the fuel cool for three days without power, small modular reactors can be designed to go without any power for weeks. He says that if the Nuclear Regulatory Commission approves a smaller emergency planning zone, that could allow Ameren to build nuclear power plants at old coal plant sites, simplifying grid connections and other siting issues.
The smaller size is also an advantage in the United States, where power demand is growing slowly and many utilities don’t want to add multiple gigawatts at a time. The modular reactors are expected to take much less time to build as well, so utilities need to forecast demand only a few years out rather than more than a decade, Cryderman says.
Yet questions remain about the viability of small nuclear reactors. While their up-front cost is lower than that of larger reactors, they might prove to cost more per kilowatt of capacity—and per kilowatt-hour of power generated.
Nuclear power plants are built large to achieve economies of scale. “Designers could make the reactors put out more power, but they didn’t have to increase the capital costs proportionally,” says John Kelly, deputy assistant secretary for nuclear reactor technologies at the Department of Energy. The hope, he says, is that building the reactors in factories will provide an alternative way to reduce costs—through mass production. The small reactors are also simpler in some ways, which can also reduce costs.
But whether those savings will be realized is uncertain. It’s not clear how many reactors need to be built before the potential savings from factory production kick in, and whether there will be enough orders for reactors to hit those numbers. For that to happen, Rosner suggests, the government may have to be the first customer, buying the reactors for military bases or government labs.
Even once the final design is approved by the NRC, costs could prove higher than expected once the plants are actually built. “Part of the problem when you start in on these things, especially with a new technology, is that all the news after you begin is bad,” says Michael Golay, a professor of nuclear science and engineering at MIT. “Things never behave in an optimized fashion.”
Even if small reactors can compete with conventional nuclear power, they still might not be able to compete with natural-gas power plants, especially in the United States, where natural gas is cheap (see “Safer Nuclear Power, at Half the Price”). Their success will depend on how much utilities think they need to hedge against a possible rise in natural-gas prices over the lifetime of a plant—and how much they believe they’ll be required to reduce carbon dioxide emissions.
“At the end of the day, we’ll build the lowest-cost option for ratepayers,” Cryderman says. “If it’s too expensive, we won’t build it.” The challenge, he says, is predicting what the lowest-cost options will be over the decades new plants will operate.

DNA Chips Target Cancer

Within a few years, DNA microarrays could help diagnose and treat this killer, perhaps even before tumors form.

 

In preparation for minor surgery, John Leventhal needed a routine chest x-ray.When the New Haven, CT, doctor joined the radiologist who was examining the film, he was shocked by what he saw: an opaque blotch deep in his lung. “As a physician,” says Leventhal, “you’re taught in medical school that when you see a mass like that, it means lung cancer.” Leventhal’s medical training also taught him that to confirm the diagnosis, his doctors would need to crack open his rib cage to get a piece of the suspect tissue that would be closely examined by a pathologist-an extremely painful and hazardous operation. The weekend before that surgery, Leventhal went off on a family ski vacation. He recalls thinking, “This is the last time I will go skiing for a long, long time.”
That was five years ago. Today the medical profession’s way of dealing with cancer could be about to change. Around the same time that Leventhal underwent
surgery, researchers at Stanford University and Santa Clara, CA-based startup Affymetrix were beginning to build the first “DNA microarrays.”More commonly known as DNA chips, these are DNAcovered silicon, glass or plastic wafers capable of analyzing thousands of genes at a time to, for example, identify the ones that are active in a sample of cells. Now these microarrays appear poised to join the war on cancer. DNA chips, predicts National Cancer Institute director Richard Klausner, are “going to have a huge effect” on the diagnosis and treatment of the disease.
One reason for the excitement is that DNA chips offer a whole new-and potentially much earlier, easier and more precise-way of detecting cancerous cells. Most forms of cancers go unnoticed until lumps, coughs or pains develop, at which point it is often too late. And even then, once a pathologist gets a biopsy from a tumor, distinguishing one form of cancer from another can be difficult or even impossible with existing techniques, which involve noting distortions in the cells’ architecture under a microscope. Better diagnostic information could be used to make better treatment decisions, perhaps making the difference between life and death.
ithin the next two years, pathologists expect to begin using DNA-chip-based tools to spot genetic differences among cells; these telltale differences could be used to help detect cancerous cells long before symptoms develop and to distinguish one type of cancer from another. In short, the chips will provide a genetic profile of a cancerous cell that can be read like a criminal’s rap sheet. The physician will know where the cancerous cell originated, how far it has progressed, and which therapies will work best to halt its further growth and spread.
Leventhal was lucky. His lung biopsy was negative, and he was back on the slopes the next winter. But it took him a month to recover from the biopsy surgery, and today he has an angry scar down the middle of his chest to remind him of the ordeal. By the end of the decade, it is likely that a patient like Leventhal will be able to skip invasive diagnostic procedures altogether. A DNA-chip-based device might be able to read a sputum sample right in the doctor’s office, checking for the genetic changes in the lung cells that are naturally sloughed off into the viscous fluid. If the news is bad, the patient might well have a host of new treatment options. That’s because DNA chips are also speeding the discovery of new and better cancer drugs. “We’re on the threshold of a new era,” says Klausner. “Technologies like DNA chips will tell us not only that something may be amiss, but what it is and what we can do about it.”

From the Labs: Biotechnology

New publications, experiments and breakthroughs in biotechnology–and what they mean. 
Magnetic Genes
Genetically ­engineered cells make their own nano magnets, providing clear MRI images
 Source: “MagA is sufficient for producing magnetic nanoparticles in mammalian cells, making it an MRI reporter”
Xiaoping P. Hu and Anthony W. S. Chan
Magnetic Resonance in Medicine
59: 1225-1231
Results: Scientists genetically engineered mammalian cells to produce magnetic particles three to five nanometers in diameter. The particles can be detected with magnetic resonance imaging (MRI), which could give scientists a novel way to track cells in the body.
Why it matters: Scientists typically use fluorescent markers to track specific cell types. But fluorescent signals can’t travel very far through animal tissue, so the approach is of limited use in live studies. Cellular labels detectable with MRI, which can see deep into the body, could allow scientists to observe a range of biological processes as they unfold in live animals.
Methods: From a pond-­dwelling bacterium, scientists isolated a gene for producing magnetic particles, which the bacterium uses like a compass. They inserted the gene into human cells and injected the cells into the brains of live mice. The mouse cells began to produce their own magnetic particles and could be seen clearly with MRI.
Next steps: The researchers will further assess how the nanoparticles could be used with MRI by better characterizing them and measuring their effect on cells–determining, for ­example, whether they are toxic or whether they alter cellular functions in living animals.


Genetically Prescribed Vitamins
Newly discovered genetic variations could predict who needs more folic acid
Source: “The prevalence of folate-remedial MTHFR enzyme variants in humans”
Nick Marini et al.
Proceedings of the National Academy of Sciences
105: 8055-8060
Results: Scientists at the University of California, Berkeley, identified several new variations in the gene for methylenetetrahydrofolate reductase (MTHFR), an enzyme that converts the B vitamin folate (called folic acid in supplements) from one form into another. They found that some variants of the enzyme need more folate to work effectively, a finding that could have implications for human nutrition.
Why it matters: Scientists hope that this type of research will eventually pave the way for individually tailored doses of vitamins. In particular, the work may help suggest who needs to take more folic acid to prevent ailments such as birth defects and possibly heart disease, which have been linked to malfunction of the MTHFR enzyme.
Methods: Researchers sequenced the MTHFR gene in 564 people of different ethnicities. Then they added the human gene sequences to yeast cells, which were engineered so that their growth rate depended on how well the enzyme was working. By feeding the yeast varying amounts of folate, the scientists could determine which of the genetic variants needed more of the vitamin to function properly.
Next steps: An ongoing human study performed in collaboration with the Children’s Hospital Oakland Research Institute and the Joint Genome Institute in Walnut Creek, CA, should provide more data on the enzyme’s role in birth defects. Scientists will sequence the gene in 250 normal children and 250 children with neural-tube defects to see whether the poorly functioning variants appear more often in the latter.

Genetically Prescribed Vitamins
Newly discovered genetic variations could predict who needs more folic acid
Source: “The prevalence of folate-remedial MTHFR enzyme variants in humans”
Nick Marini et al.
Proceedings of the National Academy of Sciences
105: 8055-8060
Results: Scientists at the University of California, Berkeley, identified several new variations in the gene for methylenetetrahydrofolate reductase (MTHFR), an enzyme that converts the B vitamin folate (called folic acid in supplements) from one form into another. They found that some variants of the enzyme need more folate to work effectively, a finding that could have implications for human nutrition.
Why it matters: Scientists hope that this type of research will eventually pave the way for individually tailored doses of vitamins. In particular, the work may help suggest who needs to take more folic acid to prevent ailments such as birth defects and possibly heart disease, which have been linked to malfunction of the MTHFR enzyme.
Methods: Researchers sequenced the MTHFR gene in 564 people of different ethnicities. Then they added the human gene sequences to yeast cells, which were engineered so that their growth rate depended on how well the enzyme was working. By feeding the yeast varying amounts of folate, the scientists could determine which of the genetic variants needed more of the vitamin to function properly.
Next steps: An ongoing human study performed in collaboration with the Children’s Hospital Oakland Research Institute and the Joint Genome Institute in Walnut Creek, CA, should provide more data on the enzyme’s role in birth defects. Scientists will sequence the gene in 250 normal children and 250 children with neural-tube defects to see whether the poorly functioning variants appear more often in the latter.

Genetically Prescribed Vitamins
Newly discovered genetic variations could predict who needs more folic acid
Source: “The prevalence of folate-remedial MTHFR enzyme variants in humans”
Nick Marini et al.
Proceedings of the National Academy of Sciences
105: 8055-8060
Results: Scientists at the University of California, Berkeley, identified several new variations in the gene for methylenetetrahydrofolate reductase (MTHFR), an enzyme that converts the B vitamin folate (called folic acid in supplements) from one form into another. They found that some variants of the enzyme need more folate to work effectively, a finding that could have implications for human nutrition.
Why it matters: Scientists hope that this type of research will eventually pave the way for individually tailored doses of vitamins. In particular, the work may help suggest who needs to take more folic acid to prevent ailments such as birth defects and possibly heart disease, which have been linked to malfunction of the MTHFR enzyme.
Methods: Researchers sequenced the MTHFR gene in 564 people of different ethnicities. Then they added the human gene sequences to yeast cells, which were engineered so that their growth rate depended on how well the enzyme was working. By feeding the yeast varying amounts of folate, the scientists could determine which of the genetic variants needed more of the vitamin to function properly.
Next steps: An ongoing human study performed in collaboration with the Children’s Hospital Oakland Research Institute and the Joint Genome Institute in Walnut Creek, CA, should provide more data on the enzyme’s role in birth defects. Scientists will sequence the gene in 250 normal children and 250 children with neural-tube defects to see whether the poorly functioning variants appear more often in the latter.

Solar Downturn Casts a Shadow Over Innovation

With no one buying new equipment, solar companies are looking to make the best of existing technology. 

Suntech employee

Suntech Power, the large Chinese solar panel maker that filed for bankruptcy last month, isn’t the only solar company teetering on the edge. Almost all of the world’s largest solar panel makers are in danger of going bankrupt within a year, and the downturn is having an impact on innovation.

A Data-Crunching Prize to Cut Flight Delays

A contest to improve flight arrival estimates is the first step in a plan to automate in-flight decisions. 

man looks at flight info on airport monitor 

A team from Singapore is taking home a $100,000 prize for developing an algorithm that could help airlines better predict flight arrival times and reduce passenger delays. The contest was sponsored by General Electric and Alaska Airlines.

The Facebook Phone Is Finally Here, but Who Wants It?

The appeal of Facebook’s new phone software may be limited to hardcore users.

                             
On Thursday morning, Mark Zuckerberg stood smiling in front of a crowd of journalists and employees at Facebook’s headquarters and put months of rumors to an end. “Today we’re finally going to talk about that Facebook phone,” he said, referring to long-swirling speculation that the social network was secretly developing a device to rival the iPhone. He immediately clarified, adding, “More accurately, we’re going to talk about how you can turn your Android phone into a great, simple, social device.”

Apple’s Next Innovation- tv

 Television viewers fumble with awkward remote controls and crave a richer array of on-demand programming. It’s time for Apple to step in and disrupt the TV business. lol!

              Steve Jobs couldn’t hide his frustration. Asked at a technology conference in 2010 whether Apple might finally turn its attention to television, he launched into an exasperated critique of TV. Cable and satellite TV companies make cheap, primitive set-top boxes that “squash any opportunity for innovation,” he fumed. Viewers are stuck with “a table full of remotes, a cluster full of boxes, a bunch of different [interfaces].” It was the kind of technological mess that cried out for Apple to clean it up with an elegant product. But Jobs professed to have no idea how his company could transform the TV.